184/18 | General Article | Veterinary Gynaecology and Obstetrics

Endometrial Healing and Recovery Rate Assessment with Bacterial Collagenase Therapy in Retained Fetal Membrane Cows

Department of Veterinary Gynaecology and Obstetrics, Madras Veterinary College, TANUVAS, Chennai- 600 007, Tamil Nadu

Abstract

The retained fetal membrane (RFM) in cows presented to Obstetrics Unit, Madras Veterinary College, and Chennai within 12 to 24 h after parturition were utilized. Group I (n=7) cows with normal calving and shedding of placenta received one litre of normal saline intravenously as placebo treatment. Group II (n=15) unassisted calving RFM cows were treated with intrauterine proteolytic bolus containing nitrofurazone, metronidazole and urea and Inj. Streptopenicillin @ 20,000 units/ kg bwt., without manual removal for 7 days. Groups III unassisted calving RFM cows (n=l5) and Group IV (n=15) difficulty in parturition RFM cows, received single dose of 2,00,000 U of collagenase plus 40 mg of calcium chloride and 40 mg of sodium bicarbonate dissolved in one litre of normal saline at a pH of 7.5 intravenously through jugular vein. The lochial epithelial cell count was significantly (P<0.01) higher in group I on day 0 than the other groups; group III and IV did not differ significantly over group I on day 7 and 14 postpartum, however group II had significantly (P<0.01) decreased lochial epithelial cell count. The lochial leucocytic count was significantly (P<0.01) higher in group IV on day 0 and group II on day 7; however on day 14, it was similar to that of day 7 in all the groups. The overall mean concentration of lochial leucocytic count was significantly (P<0.01) higher in group II.

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