269/19 | General Article | Veterinary Pharmacology and Toxicology

Evaluation of efcacy of Azithromycin and Neostigmine in the Management of Ileus in Goats

P.A. Ammu, G.Vijayakumar, S.Sivaraman, and S.Kathirvel

Department of Veterinary Clinical Medicine, Veterinary College and Research Institute, TANUVAS, Namakkal - 637 002, Tamil Nadu

Published in the Indian Veterinary Journal April 2020: 97 (4) - pages 13 to 17
(Received: July, 2019, Accepted: November, 2019)


Fifteen goats with gastrointestinal motility disorders were subjected to clinical, haematobiochemical and ultrasonographic examination as per standard techniques. The predominant clinical signs noticed in these animals were achezia, sunken eye balls, increased capillary re ll time, increased skin tent test and bilateral distension of abdomen. Elevation of mean packed cell volume, leucocytosis with neutrophilia, hypocalcaemia, hypokalemia, hypophophatemia and hypochloremia were noticed. Ultrasonography of abdomen in goats with gastrointestinal motility revealed hyperechoic and dilated loops of intestine with marked reduction or absence of motility. Goats with gastrointestinal motility disorders were administered with either azithromycin (@8.8mg/kg intravenously) or neostigmine (@0.02 mg/kg intravenously) for 3 days. It was concluded that azithromycin was effective prokinetic for management of gastrointestinal motility disorders in goats

Key Words: Goat, Gastrointestinal motility, Azithromycin, Neostigmine

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