Review Article | Veterinary Clinical Medicine

Insight to Antibiotic Resistance Under One Health Banner- A Review

Burhan Nabi, S.R. Upadhyay, Sanober Rasool, Javid Ur Rahman, Rajiv Singh, Sabeena Nabi, Omer Mohi-U-Din Sofi, and Amir Amin Sheikh

Division of Veterinary Medicine, Faculty of Veterinary Sciences and Animal Husbandry, Sher-e- Kashmir University of Agricultural Sciences & Technology, Jammu 181102

Published in the Indian Veterinary Journal June 2022 : 99 (6) - pages 7 to 15
(Received: , Accepted: )


Antibiotics are used widely in modern medicine to treat bacterial infections in humans and animals. Indiscriminate and widespread use of antibiotics has led to decreased efficacy of the antibiotics known as “antibiotic resistance”, which is defined as the capability of an organism to resist the killing effects of an antibiotic to which it was previously susceptible. The undiscerning use of antibiotics has led to a rapid surge in antibiotic resistance, consequently leading to therapeutic failure, a drop in economy, and a source of resistant gene pool transferred over to humans. In many parts of world, various antibiotics are extensively used to raise livestock and poultry. The indiscriminate use of antimicrobials in the animal sector creates drug-resistant pathogens that pose a potential threat to humans. The emergence of antibiotic resistance progressively undermines the viability of many antibiotics. If no immediate and radical actions are taken collectively against this trend, soon humans will be running out of options to save lives and the world will go backward to a pre-antibiotic era.

Key Words: Antibiotic resistance, Drug-resistant pathogens, Animal feeds, One health

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