108/19 | General Article | Veterinary Microbiology

Antiviral Activity of Ethanolic Extract of Srikaya Seeds (Annona squamosa L.) Against Avian Inuenza Virus

Maya Nurwartanti Yunita, Adi Prijo Raharjo, Prima Ayu Wibawati and Bodhi Agustono

Department of Veterinary Pathology, Faculty of Veterinary Medicine, Airlangga University, Mulyorejo st. Campus C Surabaya, East Java 60286 Indonesia

Published in the Indian Veterinary Journal September 2019 : 96 (09) - pages 26 to 29
(Received: April, 2019, Accepted: May, 2019)


Drug resistance against in uenza viruses have brought the attention of public concern. The development of new antiviral was needed. This study aim to determined the antiviral activity of ethanolic extract of srikaya seeds (EESS) on Avian in uenza (AI) when inoculated in embryonated chicken eggs by hemagglutination test. Determination of AI virus titers was carried out by chorioallantoic test. The results showed that the percentage of antiviral activity of the extract at 0.35μg/ml was 59.72%, while the extractat 0.15μg/ml and 0.25μg/ml was 33.33% and 43.06%, respectively. In conclusion, 0.35μg/ ml EESS is the most effective concentration that can inhibit the AI virus

Key Words: Antiviral activity, Avian in uenza, ethanolic extract, srikaya seeds

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