Review Article | Veterinary Clinical Medicine

Immune Response Against Mycoplasma – A Mini-review

Oveas Rafiq Parray, Rather Izhar Ul Haq, Riyaz Ahmad Bhat, Showkat Ahmad Shah, Majid Shafi Kawoosa, Amatul Muhee, Jalal Udin Parrah, Deepak Chandran, Sandip Chakraborty, Kuldeep Dhama, Mohd. Iqbal.

Faculty of Veterinary Sciences and Animal Husbandry, Shuhama, Alusteng, Srinagar, 190006, Jammu and Kashmir, India

Published in the Indian Veterinary Journal February 2022: 99 (2) - pages 14 to 20
(Received: , Accepted: )


Mycoplasmosis, caused by mycoplasma spp, is a challenging and continuous threat to livestock farming, causing huge economic and production losses. The high morbidity and mortality associated with the disease causes very high economic losses in the areas concerned with the farming of small animals, besides leads to loss of production. Treatment of the disease can lead to many concerns like development of antibiotic resistance, create carriers and also many adverse reactions which are associated with the use of these drugs. Therefore, it is important to shift our focus on the prevention and vaccination remains to be the only option for control of the disease. Many vaccines have been developed and few in developing stages. They are based on live, attenuated or killed organisms and have provided considerable immunity. However, these may have many limitations also including chances of infection, adverse reactions, or inappropriate immune response. Hence novel antigens of mycoplasma are being investigated as vaccine candidates and there is need for evaluating immune response against these antigens. The present review provides brief insights about immune response against mycoplasma vaccines or antigens.

Key Words: Mycoplasmosis, antibiotic resistance, vaccination, immune response

Main Article

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