358/19 | General Article | Veterinary Microbiology

Antibacterial Activity of Annona muricata Linn ethanolic Extraction Against Pseudomonas aeruginosa in vitro

Faisal Fikri, Imas Hapsari Rahmaningtyas and Muhammad Thohawi Elziyad Purnama

Department of Veterinary Physiology, Pharmacology and Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya 60115, Indonesia

Published in the Indian Veterinary Journal April 2020: 97 (4) - pages 38 to 40
(Received: October, 2019, Accepted: January, 2020)


This study aimed to measure antibacterial activity of Annona muricata Linn ethanolic extract on inhibition of Pseudomonas aeruginosa by diffuse disc method. The result of the inhibition zone was analyzed using contrast orthogonal Anova (p<0.01). The inhibition number of negative control (C-) was 0.00e±0.00 and the positive control (C+) was 31.31a±0.57. The result of treatment groups (T1; T2; T3; T4; T5; T6; T7; T8; T9; T10 and T11) were (14.49b±4.96; 8.98c±1.29; 5.84cd±1.85; 5.56cd±1.58; 2.85de±0.28; 2.98de±0.53; 2.82de±1.59; 2.41de±1.10; 2.20de±0.34; 1.10e±0.19 and 0.00e±0.00. It was concluded that A. muricata Linn ethanolic extract inhibits P. aeruginosa with Minimal Inhibitory Concentration (MIC) of 125 ppm

Key Words: Pseudomonas aeruginosa

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