17/21 | Research Article | Animal Genetics and Breeding

Comparative Study on Xylazine-ketamine Induced Sevoflurane and Isoflurane Anaesthesia in Rabbits (Oryctolagus cuniculus)

Vishwakarma Raj Kumari, Saumya Joshi, Yanshi and Arup Kumar Das

College of Veterinary and Animal Sciences, G.B. Pant University of Agriculture and Technology, Pantnagar - 263145, Uttarakhand

Published in the Indian Veterinary Journal January 2021 : 98 (1) - pages 13 to 18
(Received: December, 2021, Accepted: January, 2022)


Twenty healthy rabbits, of either sex, weighing 1.5 to 2.0 kg were divided into two groups (Gr-1 and Gr-2). After the routine pre-anaesthetic procedures and evaluations all rabbits were given subcutaneous injections of glycopyrrolate @ 0.01 mg/kg and xylazine @ 4 mg/kg as premedication; anaesthesia was induced with inj. ketamine (@ 40mg/kg, intramuscular). In ten rabbits of Gr-1 anaesthesia was maintained with sevoflurane-O2 mixture (2-2.5 percent) and for the other ten rabbits of Group-2, maintenance of anaesthesia were accomplished by isoflurane-O2 mixture (1-1.5 per cent) via a customized face mask, through specific vaporizers, attached to Boyles apparatus for duration of 30 minutes. It was concluded that sevoflurane and isoflurane are good inhalant anaesthetic agents for rabbits with about 20 minutes of recovery time. However, sevoflurane produced a better anaesthesia in rabbits.

Key Words: glycopyrrolate-xylazine, ketamine, sevoflurane, isoflurane, rabbits

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