280/19 | General Article | Veterinary Pharmacology and Toxicology

Photodynamic Therapy with Ozone aids to Staphylococcus aureus Bio lm Reduction

Putri S. Puspita, Suryani D. Astuti, Aulia M.T. Nasution, Anak A.S. Pradhana and Amiliyatul Mawaddah

Biophysics and Biomedical Laboratory, Department of Physics Faculty Science and Technology, Universitas Airlangga, Campus C Jl. Mulyorejo, Surabaya 60115, East Java, Indonesia

Published in the Indian Veterinary Journal February 2020: 97 (2) - pages 24 to 26
(Received: July, 2019, Accepted: October, 2019)


This study was to improve the antibacterial effect of photodynamic therapy (PDT) with ozone-added for reducing the Staphylococcus aureus biolms. PDT involves a combination of photosensitizers (curcumin and coproporphyrin) and the appropriate light source. The reduction monitored by measuring the optical density at 595nm. The results show that the reduction levels difference in PDT increases when ozone is added. The PDT treatment with ozone aids to biolms reduction compared to the PDT.

Key Words: Bio lms, Curcumin, Ozone, Photodynamic Therapy

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