330/19 | General Article | Veterinary Pharmacology and Toxicology

Immune Stimulation by Electroacupuncture at High Frequency ST36 Acupoint through SP on Hyperglycemia

William Sayogo, Jusak Nugraha, Suhariningsih, I Ketut Sudiana, Sarmanu, Paulus Liben, Rahajoe Imam Santosa and Budi Utomo

Doctoral Study Program, Faculty of Medicine, Universitas Airlangga, Surabaya 60131, Indonesia

Published in the Indian Veterinary Journal February 2020: 97 (2) - pages 12 to 14
(Received: September, 2019, Accepted: September, 2019)


Electro acupuncture (EA) with a high frequency of 100 Hertz (HZ) at ST36 (Zusanli) acupoint is capable of stimulating interferon gamma (IFN-γ) as an phagocytosis activator through substance P (SP) in hyperglycemic conditions. EA at High frequency (100 Hz) ST36 acupoint administered in hyperglycemic rats daily for seven and fourteen days consecutively. Examination of SP and IFN-γ levels using enzyme linked immunosorbent assay (ELISA) method with blood serum. The results indicated that EA with high frequency of 100 Hz on ST36 able to increase IFN-γ through SP.

Key Words: Electroacupuncture, ST36, substance P, interferon gamma

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