48/23 | Research Article | Veterinary Biochemistry

Mucosal Immunoglobulin IgT at Gilthead Seabream Gill Plays a Predominant Role of Immunity during Vibrio harveyi Infection

Chen Meng-Han*, and Wang Chung Ping

Institute of biochemistry, Academica Sinica, Taiwan

Published in the Indian Veterinary Journal April 2023 : 100 (4) - pages 36 to 44
(Received: , Accepted: )


Teleost gill is considered a mucosal surface and a major site for pathogen entry. This study elucidated the predominant role of IgT, a primitive immunoglobulin class specialized in mucosal immunity, in the gill of gilthead seabream during V. harveyi infection. Results showed that gill bacteria cells were mainly coated by IgT upon V. harveyi infection. An increase of IgT+ B cells and IgT concentration in gill mucus were also observed. Gilthead seabream devoid of IgT had significant increase of gill bacterial load and became highly susceptible to V. harveyi infection. Taken together, this study demonstrated that IgT plays a predominant role in the antibacterial immunity of gilt head seabream gill.

Key Words: Mucosal Immunoglobulin, Gilthead Seabream Gill Plays Infection

Main Article

Access to the IVJ Digital Archives is restricted to our paid subscribers. Please consider becoming a subscriber to continue reading this article.